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Avoid concomitant use of Plavix with omeprazole or esomeprazoleIn clinical studiesomeprazole was shown to reduce significantly the antiplatelet activity of Plavix when given concomitantly or 12 hours apartA similar reduction in antiplatelet activity was observed with esomeprazole when given concomitantly with PlavixDexlansoprazolelansoprazole and pantoprazole had less effect on the antiplatelet activity of Plavix than did omeprazole or esomeprazolesee WARNINGS AND PRECAUTIONS and CLINICAL PHARMACOLOGY

If you need surgery or dental worktell the surgeon or dentist ahead of time that you take Plavix.

The observed can you snort baclofen 10 mg. risk of bleeding events with Plavix plus aspirin versus placebo plus aspirin by age category is provided in Table 1 and Table 2 for the CURE and COMMIT trialsrespectivelysee ADVERSE REACTIONSNo dosage adjustment is necessary in elderly patients.

Figure 2Cardiovascular DeathMyocardial Infarctionand Stroke in the CURE Study.

Clopidogrel was not genotoxic in four in vitro testsAmes testDNA-repair test in rat hepatocytesgene mutation assay in Chinese hamster fibroblastsand metaphase chromosome analysis of human lymphocytesand in one in vivo testmicronucleus test by oral route in mice

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my dad is 60 and has been on plavix for 7 years never caused him a problem because he was diagnosed back then with angina.


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